Rivnuts from Homestead,PA on 11/13/2022 4:43:16 PM:
I’ve ridden self-supported from Harpers Ferry to the train station at the end of the W&OD in Purcellville a few years ago. I followed the bicycle route that Google Maps yields between these two locations which is:
(There aren’t a lot of options.)
Rte 340 was easily the the diciest, albeit the shortest route, of all with heavy, high-speed traffic and rubble in the shoulder. The others were country highways with less traffic and rolling hills.
Perhaps other forum contributors can offer some other options or feedback.
Although not directly related to your question and you likely already know, you’ll need to carry your bike up the stairs from the C&O Towpath to the railroad/pedestrian bridge to Harper’s Ferry.